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Article

Are false negative direct immnufluorescence assays caused by varicella zoster virus gE mutant strains?

Journal of medical virology - 1 Aug 2004

Taha Yusri A, Quinlivan Mark, Scott Fiona T, Leedham-Green Mary, Hawrami Khidir, Thomas Janice M, Breuer Judith

Abstract excerpt

Strains of Varicella zoster virus (VZV) have been described recently in which a single base mutation in the gE epitope abrogates binding of the 3B3 monoclonal antibody, which is widely used for virus detection in diagnostic laboratories. These strains, named VZV-MSP, are associated with a distinct phenotype in both in vitro culture and in SCID-hu mice. We investigated the possibility that negative direct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15221911
DOI: 10.1002/jmv.20137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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