Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ORF7 of Varicella-Zoster Virus Is a Neurotropic Factor

7 Jun 2012

Abstract excerpt

Varicella-zoster virus (VZV) is the causative agent of chickenpox and herpes zoster (shingles). After the primary infection, the virus remains latent in sensory ganglia and reactivates upon weakening of the cellular immune system due to various conditions, erupting from sensory neurons and infecting the corresponding skin tissue. The current varicella vaccine is highly attenuated in the skin and yet retains its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Herpesvirus Infections and Treatments
Share to Poxvirus research and outbreaks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22674980
DOI: 10.1128/jvi.00128-12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ORF7 of Varicella-Zoster Virus Is a Neurotropic FactorPMID 22674980Read ↗

Genome-Wide Mutagenesis Reveals That ORF7 Is a Novel VZV Skin-Tropic FactorSemantic proximity Read ↗

ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal CellsSemantic proximity Read ↗

A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infectionSemantic proximity Read ↗

ORF9p phosphorylation by ORF47p is crucial for the formation and egress of varicella-zoster virus viral particles.Semantic proximity Read ↗

The live attenuated varicella-zoster virus vaccine vOka: Molecular and cellular biology of its skin attenuationSemantic proximity Read ↗

Varicella zoster virus: out of Africa and into the research laboratory.Semantic proximity Read ↗

Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infection.Semantic proximity Read ↗

Functions of the ORF9-to-ORF12 Gene Cluster in Varicella-Zoster Virus Replication and in the Pathogenesis of Skin InfectionSemantic proximity Read ↗

Varicella-Zoster Virus Glycoprotein E Is a Critical Determinant of Virulence in the SCID Mouse-Human Model of NeuropathogenesisSemantic proximity Read ↗

The attenuated genotype of varicella-zoster virus includes an ORF0 transitional stop codon mutation.Semantic proximity Read ↗

Clinical and molecular aspects of the live attenuated Oka varicella vaccineSemantic proximity Read ↗

Functions of the C-Terminal Domain of Varicella-Zoster Virus Glycoprotein E in Viral Replication In Vitro and Skin and T-Cell Tropism In VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.