Article
Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D.
Journal of clinical microbiology - 1 Jan 2008
Schmidt-Chanasit Jonas, Bleymehl Karoline, Schäd Susanne G, Gross Gerd, Ulrich Rainer G, Doerr Hans Wilhelm
Abstract excerpt
Here, we describe the association of certain varicella-zoster virus (VZV) genotypes with unique glycoprotein E (gE) gene mutations. Within 45 analyzed VZV wild-type strains of genotypes A and D, five novel gE mutations were discovered. A statistically significant (P < 0.0001) association of certain gE mutations with VZV genotype D was found.
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