Article
Association of maternal angiotensin II type 1 and type 2 receptor combination genotypes with susceptibility to early-onset preeclampsia.
Journal of human hypertension - 1 Mar 2022
Satra M, Samara M, Alatsathianos G, Vamvakopoulou D, Baka A, Tsalazidou-Founta T-M, Sidiropoulos A, Vamvakopoulos K-O, Garas A, Daponte A, Vamvakopoulos N, Sotiriou S
Abstract excerpt
Allelic variations affecting the activity of the maternal renin-angiotensin system may play a role in the development of hypertensive disorders of pregnancy like preeclampsia, its more severe early-onset form, and intrauterine growth restriction. We examined the association of common allelic variants of angiotensin II type 1 and type 2 receptor genes (AT1R and AT2R) sorted in five AT1R/AT2R receptor combination...
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