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Article

Malignant transformation of endometriosis: application of laser microdissection for analysis of genetic alterations according to pathological changes.

Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan - 1 Jun 2004

Sekizawa Akihiko, Amemiya Satoshi, Otsuka Junko, Saito Hiroshi, Farina Antonio, Okai Takashi, Tachikawa Tetsuhiko

Abstract excerpt

Endometriosis is considered to be a possible precancerous disease. Pathologically, we observed malignant transformation of endometriosis to clear cell carcinoma or endometriotic carcinoma of the ovary, via the step of atypical endometriosis. Pathological changes reflected genetic alterations. In cases of clear cell carcinoma, we assessed K- ras mutations in regions of normal endometriosis, atypical endometriosis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15221651
DOI: 10.1007/s00795-003-0233-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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