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Article

Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis.

Human reproduction update - 1 Jan 2000

Viganó Paola, Somigliana Edgardo, Chiodo Ilda, Abbiati Annalisa, Vercellini Paolo

Abstract excerpt

Although population-based studies have unequivocally reported an increased risk of ovarian cancer in women with endometriosis, the biological evidence supporting the idea of endometriosis as a preneoplastic condition is scanty and not well substantiated. The fundamental features of human neoplasms (monoclonal growth, genetic changes, mutations in tumour suppressor genes and replicative advantage) have been...

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PMID: 16172112
DOI: 10.1093/humupd/dmi037

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PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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