Article
Genotypes of ALDH2 related to liver and pulmonary diseases and other genetic factors related to alcoholic liver disease.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Nov 1994
Takada A, Tsutsumi M, Kobayashi Y
Abstract excerpt
Genetic factors related to the development of alcoholic liver and pancreatic diseases (ALD and APD) and of alcohol-induced asthma were analyzed. The development of ALD is genetically controlled and is directly associated with the polymorphisms of the genes of acetaldehyde (Ac-CHO) and ethanol-met...
Topics
- Acetaldehyde
- Aldehyde Dehydrogenase
- Asthma
- Cytochrome P-450 CYP2E1
- Cytochrome P-450 Enzyme System
- Enzyme Induction
- Genetic Linkage
- Genotype
- Humans
- Isoenzymes
- Liver Diseases, Alcoholic
- Lung Diseases, Obstructive
