Article
Genotypes of ALDH2 related to liver and pulmonary diseases and other genetic factors related to alcoholic liver disease.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Nov 1994
Takada A, Tsutsumi M, Kobayashi Y
Abstract excerpt
Genetic factors related to the development of alcoholic liver and pancreatic diseases (ALD and APD) and of alcohol-induced asthma were analyzed. The development of ALD is genetically controlled and is directly associated with the polymorphisms of the genes of acetaldehyde (Ac-CHO) and ethanol-metabolizing enzymes, aldehyde dehydrogenase-2 (ALDH2) and cytochrome P4502E1. The development of ALD and APD may also be...
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