Article
Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease.
Acta biochimica Polonica - 1 Jan 2004
Hannan Anthony J
Abstract excerpt
Huntington's disease (HD) is an autosomal dominant disorder in which there is progressive neurodegeneration producing motor, cognitive and psychiatric symptoms. HD is caused by a trinucleotide (CAG) repeat mutation, encoding an expanded polyglutamine tract in the huntingtin protein. At least eigh...
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