Article
Transcriptional response of yeast to aflatoxin B1: recombinational repair involving RAD51 and RAD1.
Molecular biology of the cell - 1 Sept 2004
Keller-Seitz Monika U, Certa Ulrich, Sengstag Christian, Würgler Friedrich E, Sun Mingzeng, Fasullo Michael
Abstract excerpt
The potent carcinogen aflatoxin B(1) is a weak mutagen but a strong recombinagen in Saccharomyces cerevisiae. Aflatoxin B(1) exposure greatly increases frequencies of both heteroallelic recombination and chromosomal translocations. We analyzed the gene expression pattern of diploid cells exposed to aflatoxin B(1) using high-density oligonucleotide arrays comprising specific probes for all 6218 open reading...
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