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Article

Molecular characterization of benzimidazole resistance in Helicobacter pylori.

Antimicrobial agents and chemotherapy - 1 Jul 2004

Mills Scott D, Yang Wei, MacCormack Kathleen

Abstract excerpt

A family of benzimidazole derivatives (BI) was shown to possess potent and selective activity against Helicobacter pylori, although the precise cellular target of the BIs is unknown. Spontaneous H. pylori mutants were isolated as resistant to a representative BI (compound A). Genomic DNA was isolated from a BI-resistant mutant, transformed into a BI-sensitive strain, and found to be sufficient to confer BI...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15215104
DOI: 10.1128/AAC.48.7.2524-2530.2004
PMCID: PMC434220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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