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Article

In vitro anti-Helicobacter pylori activity and phenotypic screening of novel quinolone compounds.

Archives of microbiology - 20 Nov 2025

Wang Yuan-Yuan, Mou Guo-Liang, Chen Xing-Lan, Yang Jin-Xia, Luo Qian, Dong Ye-Ze, Xie Bao-Yuan, Zhang De-Kui, Liu Ying-Qian

Abstract excerpt

Helicobacter pylori (H. pylori) is a widespread pathogen and a significant causative agent of chronic gastritis and peptic ulcers. However, eradication rates are declining rapidly because of increasing antibiotic resistance, and recurrence rates are rising. Quinolone-based regimens were once considered effective treatment options; however, their clinical utility has been substantially limited in recent years by a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41264022
DOI: 10.1007/s00203-025-04583-x

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