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Article

Association of Megsin Gene Variants With IgA Nephropathy in Northwest Chinese Population: A STROBE-Compliant Observational Study.

Medicine - 1 Feb 2016

Wei Lin-Ting, Fu Rong-Guo, Gao Jie, Yu Qiao-Ling, Dong Feng-Ming, Wang Zhe, Wang Meng, Liu Xing-Han, Dai Zhi-Jun

Abstract excerpt

Megsin is a mesangial cell-predominant gene that encodes a serpin family protein which is expressed in the renal mesangium. Overexpression of megsin has been observed in the glomeruli of patients with IgA nephropathy (IgAN). The aim of this study was to evaluate the association of megsin polymorphisms (rs1055901 and rs1055902) with IgAN in a Chinese population.We examined 351 patients with histologically proven...

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Identifiers

PMID: 26871801
DOI: 10.1097/MD.0000000000002694
PMCID: PMC4753896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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