Article
Mutations affecting retinotectal axonal pathfinding in Medaka, Oryzias latipes.
Mechanisms of development - 1 Jul 2004
Yoda Hiroki, Hirose Yukihiro, Yasuoka Akihito, Sasado Takao, Morinaga Chikako, Deguchi Tomonori, Henrich Thorsten, Iwanami Norimasa, Watanabe Tomomi, Osakada Masakazu, Kunimatsu Sanae, Wittbrodt Joachim, Suwa Hiroshi, Niwa Katsutoshi, Okamoto Yasuko, Yamanaka Toshiyuki, Kondoh Hisato, Furutani-Seiki Makoto
Abstract excerpt
We screened for mutations affecting retinotectal axonal projection in Medaka, Oryzias latipes. In wild-type Medaka embryos, all the axons of retinal ganglion cells (RGCs) project to the contralateral tectum, such that the topological relationship of the retinal field is maintained. We labeled RGC axons using DiI/DiO at the nasodorsal and temporoventral positions of the retina, and screened for mutations affecting...
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