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Article

Drosophila mutants of the kynurenine pathway as a model for ageing studies.

Advances in experimental medicine and biology - 1 Jan 2003

Savvateeva-Popova Elena V, Popov Andrey V, Heinemann Thoralf, Riederer Peter

Abstract excerpt

A search for Drosophila mutants with phenotypes similar to human diseases might help to unravel evolutionary conserved genes implicated in polygenic human disorders. Among these are neurodegenerative diseases, characterized by a late onset disturbance of memory, structural brain impairments and altered content of the intermediates of the kynurenine pathway. The ratio between kynurenate (KYNA) and...

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PMID: 15206794
DOI: 10.1007/978-1-4615-0135-0_84

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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