Article
Age-dependent changes in memory and mushroom bodies in the Drosophila mutant vermilion deficient in the kynurenine pathway of tryptophan metabolism.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 Jan 1999
Savvateeva E V, Popov A V, Kamyshev N G, Iliadi K G, Bragina J V, Heisenberg M, Kornhuber J, Riederer P
Abstract excerpt
Evolutionary conservation of homologous genes that cause related phenotypes in humans and Drosophila help to unravel genes implicated in polygenic human diseases. Among them are neurodegenerative disorders, such as Huntington, Parkinson, Alzheimer and HIV-induced diseases. They are characterized by a late onset disturbances of memory, changes in volumetric indices of the brain structures involved in memory...
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