Article
Modulation of sensory information processing by a neuroglobin in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jun 2017
Oda Shigekazu, Toyoshima Yu, de Bono Mario
Abstract excerpt
Sensory receptor neurons match their dynamic range to ecologically relevant stimulus intensities. How this tuning is achieved is poorly understood in most receptors. The roundworm Caenorhabditis elegans avoids 21% O2 and hypoxia and prefers intermediate O2 concentrations. We show how this O2 preference is sculpted by the antagonistic action of a neuroglobin and an O2-binding soluble guanylate cyclase. These...
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