Article
Lack of association of CCR4 single nucleotide polymorphism with atopic dermatitis in Japanese patients.
Acta dermato-venereologica - 1 Jan 2004
Tsunemi Yuichiro, Sekiya Takashi, Saeki Hidehisa, Hirai Koichi, Ohta Ken, Nakamura Koichiro, Kakinuma Takashi, Fujita Hideki, Kagami Shinji, Asano Noriko, Tanida Yuka, Wakugawa Motoshi, Torii Hideshi, Tamaki Kunihiko
Abstract excerpt
CCR4, a member of the CC chemokine receptor family, is believed to play an important role in the pathogenesis of atopic dermatitis. To examine whether CCR4 single nucleotide polymorphism (SNP) is associated with susceptibility to atopic dermatitis, we investigated the allele and genotype frequencies of C1014T SNP of CCR4 in 198 Japanese patients with atopic dermatitis and controls by a PCR-restriction fragment...
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