Article
Lack of association between HLA-DQ and -DR genotypes and asthma in southern Chinese patients.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 1995
Li P K, Lai C K, Poon A S, Ho A S, Chan C H, Lai K N
Abstract excerpt
Asthma is an inflammatory disease with a strong genetic predisposition. We have studied a group of unrelated asthmatic patients of southern Chinese origin on their HLA-DR and -DQ regions using molecular techniques and compared them with 104 healthy controls of the same ethnic origin. Restriction fragment length polymorphism (RFLP) was used to genotype the MHC class II DR beta, DQ alpha and DQ beta loci of the...
Topics
- Adolescent
- Adult
- Aged
- Asthma
- China
- Female
- Genotype
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Male
- Middle Aged