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Article

Rat transgenic models with a phenotype of intracellular Abeta accumulation in hippocampus and cortex.

Journal of Alzheimer's disease : JAD - 1 Jun 2004

Echeverria Valentina, Ducatenzeiler Adriana, Alhonen Leena, Janne Juhani, Grant Susan M, Wandosell Francisco, Muro Andres, Baralle Francisco, Li Hongshan, Duff Karen, Szyf Moshe, Cuello A Claudio

Abstract excerpt

In this communication we report the characterization of several transgenic rat lines expressing human AbetaPP carrying the Swedish and Indiana mutations (coded UKUR28), the human presenilin 1 transgene with the 'Finn' mutation (coded UKUR19) and double transgenic rats expressing both transgenes (coded UKUR25). In these Tg rats, the AbetaPP and PS1 transgene expression was largely restricted to the hippocampus and...

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Share to Amyloid beta-Protein Precursor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15201476
DOI: 10.3233/jad-2004-6301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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