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Article

A minimal length between tau exon 10 and 11 is required for correct splicing of exon 10.

Journal of neurochemistry - 1 Jul 2004

Yu Qingming, Guo Jun, Zhou Jianhua

Abstract excerpt

Mutations that stimulate exon 10 inclusion into the human tau mRNA cause frontotemporal dementia with parkinsonism, associated with chromosome 17 (FTDP-17), and other tauopathies. This suggests that the ratio of exon 10 inclusion to exclusion in adult brain is one of the factors to determine biological functions of the tau protein. To investigate the underlying splicing mechanism and identify potential...

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Identifiers

PMID: 15198676
DOI: 10.1111/j.1471-4159.2004.02477.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A minimal length between tau exon 10 and 11 is required for correct splicing of exon 10.PMID 15198676Read ↗

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5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10.Semantic proximity Read ↗

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