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Article

Signaling pathways weigh in on decisions to make or break skeletal muscle

10 Jun 2004

Abstract excerpt

PURPOSE OF REVIEW: Regulation of muscle size is essential for proper development and homeostasis of adult musculature. This regulation is mediated in large part by signal transduction pathways that promote the synthesis or breakdown of skeletal muscle. PI(3)K/Akt, myostatin and NF-kappaB represent three such pathways that will be the focus of this review. RECENT FINDINGS: Recent reports solidify the requirement...

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PMID: 15192448
DOI: 10.1097/01.mco.0000134364.61406.26

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