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Article

Metallothionein-III prevents gamma-ray-induced 8-oxoguanine accumulation in normal and hOGG1-depleted cells.

The Journal of biological chemistry - 13 Aug 2004

Jeong Hye Gwang, Youn Cha-Kyung, Cho Hyun-Ju, Kim Soo-Hyun, Kim Mi-Hwa, Kim Hong-Beum, Chang In-Youb, Lee Yun-Sil, Chung Myung-Hee, You Ho Jin

Abstract excerpt

Metallothioneins (MT) play an important biological role in preventing oxidative damage to cells. We have previously demonstrated that the efficiency of the protective effect of MT-III against the DNA degradation from oxidative damage was much higher than that of MT-I/II. As an extension of the latter investigation, this study aimed to assess the ability of MT-III to suppress 8-oxoguanine (8-oxoG), which is one of...

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Source

Identifiers

PMID: 15190073
DOI: 10.1074/jbc.M402530200

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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