Article
Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope.
Arthritis and rheumatism - 1 Jun 2004
Prokunina Ludmila, Padyukov Leonid, Bennet Anna, de Faire Ulf, Wiman Björn, Prince Jonathan, Alfredsson Lars, Klareskog Lars, Alarcón-Riquelme Marta
Abstract excerpt
OBJECTIVE: To study the frequency of allele A of polymorphism PD-1.3 of the PDCD1 gene in patients with rheumatoid arthritis (RA) and its subsets, based on the presence of rheumatoid factor (RF) and the shared epitope (SE) alleles. METHODS: A total of 1,175 patients with RA and 3,404 controls were genotyped for the PD-1.3 A/G polymorphism, which previously was identified as being involved in susceptibility to...
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