Article
A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese.
Arthritis and rheumatism - 1 Apr 2005
Kong Eric Kai-Pang, Prokunina-Olsson Ludmila, Wong Wilfred Hing-Sang, Lau Chak-Sing, Chan Tak-Mao, Alarcón-Riquelme Marta, Lau Yu-Lung
Abstract excerpt
OBJECTIVE: The programmed death 1 (PD-1) molecule is a negative regulator of T cells, and a genetic association between PD-1 and systemic lupus erythematosus and rheumatoid arthritis (RA) in Caucasians has been reported. The aim of this study was to investigate the association of PDCD1 polymorphisms and haplotypes with RA in the Chinese population. METHODS: Three single-nucleotide polymorphisms (SNPs), PD-1.1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
