Article
Evaluation of TNF-alpha and IL-1beta polymorphisms in Taiwan Chinese patients with pterygium.
Eye (London, England) - 1 May 2005
Tsai Y-Y, Lee H, Tseng S-H, Cheng Y-W, Tsai C-H, Hsu C-M, Tsai F-J
Abstract excerpt
PURPOSE: Pterygium, a complex disease, is associated with ultraviolet radiation, immunoinflammatory process, genetic factors, and virus infection. Ultraviolet radiation induces secretion of proinflammatory cytokines by the ocular surface epithelium, inflammatory cells in the tear fluid, or both. Among these cytokines, tumour necrosis factor (TNF)alpha and interleukin (IL)-1beta activate pterygium body...
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