Article
AI-2 quorum sensing affects antibiotic susceptibility in Streptococcus anginosus.
The Journal of antimicrobial chemotherapy - 1 Jul 2007
Ahmed Nibras A A M, Petersen Fernanda C, Scheie Anne Aamdal
Abstract excerpt
OBJECTIVES: The concern over rising antibiotic resistance necessitates exploration of alternative approaches in antimicrobial therapy. Bacterial communities use the auto-inducer 2 (AI-2) quorum sensing signal at a specific threshold level for intra- and interspecies communication in order to regulate virulence behaviour. AI-2 signal production occurs in bacteria that possess a luxS homologue. In this study, we...
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