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Article

Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation.

Journal of medical microbiology - 1 Jul 2004

Stapper Andres Plata, Narasimhan Giri, Ohman Dennis E, Barakat Johnny, Hentzer Morten, Molin Søren, Kharazmi Arsalan, Høiby Niels, Mathee Kalai

Abstract excerpt

Extracellular polymers can facilitate the non-specific attachment of bacteria to surfaces and hold together developing biofilms. This study was undertaken to qualitatively and quantitatively compare the architecture of biofilms produced by Pseudomonas aeruginosa strain PAO1 and its alginate-overproducing (mucA22) and alginate-defective (algD) variants in order to discern the role of alginate in biofilm formation....

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Source

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PMID: 15184541
DOI: 10.1099/jmm.0.45539-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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