Article
Spatial transcriptomes within the Pseudomonas aeruginosa biofilm architecture.
Molecular microbiology - 1 Dec 2017
Heacock-Kang Yun, Sun Zhenxin, Zarzycki-Siek Jan, McMillan Ian A, Norris Michael H, Bluhm Andrew P, Cabanas Darlene, Fogen Dawson, Vo Hung, Donachie Stuart P, Borlee Bradley R, Sibley Christopher D, Lewenza Shawn, Schurr Michael J, Schweizer Herbert P, Hoang Tung T
Abstract excerpt
Bacterial cooperative associations and dynamics in biofilm microenvironments are of special interest in recent years. Knowledge of localized gene-expression and corresponding bacterial behaviors within the biofilm architecture at a global scale has been limited, due to a lack of robust technology to study limited number of cells in stratified layers of biofilms. With our recent pioneering developments in single...
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