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Article

Using hierarchical modeling in genetic association studies with multiple markers: application to a case-control study of bladder cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2004

Hung Rayjean J, Brennan Paul, Malaveille Christian, Porru Stefano, Donato Francesco, Boffetta Paolo, Witte John S

Abstract excerpt

BACKGROUND: Genetic association studies are generating much information, usually in the form of single nucleotide polymorphisms in candidate genes. Analyzing such data is challenging, and raises issues of multiple comparisons and potential false-positive associations. Using data from a case-control study of bladder cancer, we showed how to use hierarchical modeling in genetic epidemiologic studies with multiple...

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PMID: 15184258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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