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Article

Sequence analysis of ADARB1 gene in patients with familial bipolar disorder.

Journal of affective disorders - 1 Jul 2004

Amore Mario, Strippoli Pierluigi, Laterza Caterina, Tagariello Pietro, Vitale Lorenza, Casadei Raffaella, Frabetti Flavia, Canaider Silvia, Lenzi Luca, D'Addabbo Pietro, Carinci Paolo, Torroni Arianna, Ferrari Giuseppe, Zannotti Maria

Abstract excerpt

BACKGROUND: The ADARB1 gene is located in 21q22.3 region, previously linked to familial bipolar disorder, and its product has a documented action in the editing of the pre-mRNA of glutamate receptor B subunit. Dysfunction of glutamatergic neurotransmission could play an important role in the pathophysiology of bipolar disorder (BD). Glutamate excitatory neurotransmission regulation is a possible mechanism of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15183604
DOI: 10.1016/j.jad.2003.08.006

Genes

ADARB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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