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Article

A 40 kDa isoform of the type 5 adenovirus IVa2 protein is sufficient for virus viability.

Virology - 20 Jun 2004

Pardo-Mateos Almudena, Young C S H

Abstract excerpt

The multifunctional IVa2 protein is essential for adenovirus replication [J. Virol. 77 (2003) 3586], but the relative importance of the transcriptional and encapsidation functions is unknown. As part of a study of IVa2 function, we created a set of mutations in the IVa2 gene in the correct location in the viral genome. Unexpectedly, an opal stop codon at position 6 was recovered in virus twice. Isolate #2 showed...

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Identifiers

PMID: 15183062
DOI: 10.1016/j.virol.2004.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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