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Article

[Study on the gene mutation of quinolone-resistant Mycobacterium tuberculosis isolated from Sichuan Province].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 May 2004

Zhao Ming-cai, Bao Lang, Wu Yue-han, Long Yang, Zeng Xian-wu, Zhang Hui-dong, Xie Yi-xin

Abstract excerpt

OBJECTIVE: To investigate the molecular mechanism of quinolone-resistance of M. tuberculosis and characterize the gene mutation in Sichuan Province. METHODS: Susceptibility of the clinical isolates to quinolones (ofloxacin, ciprofloxacin and sparfloxacin) was tested by the absolute concentration method. GyrA gene quinolone reasistance-determining region (QRDR) mutations M. tuberculosis were detected with PCR-SSCP...

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Identifiers

PMID: 15181822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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