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Article

CYP1A1 alleles in women with focal nodular hyperplasia of the liver (FNH).

International journal of clinical pharmacology and therapeutics - 1 Feb 2004

Lazar A, Menzel H, Cascorbi I, Kümel G, Sachs M, Rietbrock S, Roots I, Fuhr U

Abstract excerpt

OBJECTIVE: Disorders of steroid hormone metabolism might be related to the etiology of focal nodular hyperplasia of the liver (FNH), a benign tumor, especially prevalent in women. The cytochrome P450 1A1 (CYP1A1) enzyme is implicated in the bioactivation of multiple precarcinogens as well as in the metabolism of steroids. Genetic polymorphisms of CYP1A1 have been associated with altered catalytic activity in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15180167
DOI: 10.5414/cpp42078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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