Article
Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma.
Journal of hepatology - 1 Jan 2008
Rebouissou Sandra, Bioulac-Sage Paulette, Zucman-Rossi Jessica
Abstract excerpt
Focal nodular hyperplasia (FNH) and hepatocellular adenomas (HCAs) are benign tumors that occur in otherwise normal liver parenchyma. FNH is considered to be the result of a hyperplastic response to increased blood flow secondary to vascular malformations. Most FNH are polyclonal and to date, the molecular pathway and mechanisms that are altered in FNH have yet to be elucidated. In contrast, HCAs are consistently...
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