Article
Functional integration of embryonic stem cell-derived neurons in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Jun 2004
Wernig Marius, Benninger Felix, Schmandt Tanja, Rade Monika, Tucker Kerry L, Büssow Heinrich, Beck Heinz, Brüstle Oliver
Abstract excerpt
Pluripotency and the potential for continuous self-renewal make embryonic stem (ES) cells an attractive donor source for neuronal cell replacement. Despite recent encouraging results in this field, little is known about the functional integration of transplanted ES cell-derived neurons on the single-cell level. To address this issue, ES cell-derived neural precursors exhibiting neuron-specific enhanced green...
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