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Article

Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord.

Experimental neurology - 1 Oct 2002

Han Steve S W, Kang Diana Y, Mujtaba Tahmina, Rao Mahendra S, Fischer Itzhak

Abstract excerpt

Multipotent neural stem cells (NSCs) have the potential to differentiate into neuronal and glial cells and are therefore candidates for cell replacement after CNS injury. Their phenotypic fate in vivo is dependent on the engraftment site, suggesting that the environment exerts differential effects on neuronal and glial lineages. In particular, when grafted into the adult spinal cord, NSCs are restricted to the...

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Identifiers

PMID: 12429183
DOI: 10.1006/exnr.2002.7995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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