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Article

Adult bone marrow stromal cells in the embryonic brain: engraftment, migration, differentiation, and long-term survival.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 May 2004

Muñoz-Elias Guillermo, Marcus Akiva J, Coyne Thomas M, Woodbury Dale, Black Ira B

Abstract excerpt

We recently differentiated adult rat and human bone marrow stromal cells (MSCs) into presumptive neurons in cell culture. To determine whether the MSCs assume neuronal functions in vivo, we now characterize for the first time engraftment, migration, phenotypic expression, and long-term survival after infusion into embryonic day 15.5 (E15.5) rat ventricles in utero. By E17.5, donor cells formed discrete spheres in...

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Identifiers

PMID: 15140930
DOI: 10.1523/JNEUROSCI.5060-03.2004
PMCID: PMC6729389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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