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Article

Mapping a chromosomal locus for valproic acid-induced exencephaly in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2004

Lundberg Yunxia Wang, Cabrera Robert M, Greer Kimberly A, Zhao Jian, Garg Rohit, Finnell Richard H

Abstract excerpt

Human neural tube defects (NTDs) are among the most common congenital defects. They have a highly heterogeneous etiology, and, in addition to those seen in association with genetic syndromes, there are also NTDs induced by pharmaceutical compounds in utero, such as the widely used anti-epileptic drug valproic acid (VPA). Although familial studies have suggested a genetic contribution to VPA-induced NTDs, this...

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Identifiers

PMID: 15170225
DOI: 10.1007/s00335-004-2345-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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