Article
Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous metaplastic epithelium of bronchial airways.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jun 2004
Aarbiou J, van Schadewijk A, Stolk J, Sont J K, de Boer W I, Rabe K F, van Krieken J H J M, Mauad T, Hiemstra P S
Abstract excerpt
OBJECTIVE: The aim of this study was to analyze a possible contribution of human neutrophil defensins and secretory leukocyte proteinase inhibitor (SLPI) to the induction of airway epithelial changes such as squamous cell metaplasia. MATERIALS AND METHODS: The presence of these molecules and the number of proliferating (Ki-67-positive) epithelial cells was analyzed by immunohistochemistry in bronchial epithelium...
Topics
- Adult
- Aged
- Aged, 80 and over
- Bronchi
- Carcinoma, Squamous Cell
- Cell Proliferation
- Defensins
- Epithelium
- Female
- Humans
- Image Processing, Computer-Assisted
- Immunohistochemistry
- Ki-67 Antigen