Article
Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous metaplastic epithelium of bronchial airways.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jun 2004
Aarbiou J, van Schadewijk A, Stolk J, Sont J K, de Boer W I, Rabe K F, van Krieken J H J M, Mauad T, Hiemstra P S
Abstract excerpt
OBJECTIVE: The aim of this study was to analyze a possible contribution of human neutrophil defensins and secretory leukocyte proteinase inhibitor (SLPI) to the induction of airway epithelial changes such as squamous cell metaplasia. MATERIALS AND METHODS: The presence of these molecules and the number of proliferating (Ki-67-positive) epithelial cells was analyzed by immunohistochemistry in bronchial epithelium...
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