Article
Neutrophil Defensins Enhance Lung Epithelial Wound Closure and Mucin Gene Expression <i>In Vitro</i>
21 Jul 2003
Abstract excerpt
Human airways are frequently exposed to potentially harmful agents that cause tissue injury. Upon such injury, a repair process is initiated that comprises cell migration, proliferation, and differentiation. We have previously shown that human neutrophil defensins (human neutrophil peptides 1-3 [HNP1-3]) induce airway epithelial cell proliferation. Because of the role of cell proliferation in epithelial wound...
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