Article
Resistance to scrapie in PrP ARR/ARQ heterozygous sheep is not caused by preferential allelic use.
Journal of clinical pathology - 1 Jun 2004
Caplazi P A, O'Rourke K I, Baszler T V
Abstract excerpt
BACKGROUND: In sheep, susceptibility to scrapie, which is similar to human prion diseases such as Kuru and variant Creutzfeldt-Jakob disease (vCJD), is determined by prion protein (PrP) gene (Prnp) polymorphisms. Sheep with genotype ARQ/ARQ, denoting polymorphisms at codons 136, 154, and 171, are...
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