Article
Neuronal Migration, Cerebral Cortical Development, and Cerebral Cortical Anomalies
1 Jan 2002
Abstract excerpt
Cerebral cortical malformations are relatively common anomalies identified by neuroimaging and pathologically in patients with epilepsy and mental retardation. A disruption in neuronal migration during central nervous system development has been postulated as the pathogenesis for many of these disorders. Recently, the cell migration hypothesis has been proven accurate for lissencephaly, subcortical band...
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