Article
Fatal liver failure due to reactivation of lamivudine-resistant HBV mutant.
World journal of gastroenterology - 1 Jun 2004
Kagawa Tatehiro, Watanabe Norihito, Kanouda Hisashi, Takayama Ichiro, Shiba Tadahiko, Kanai Takashi, Kawazoe Kazuya, Takashimizu Shinji, Kumaki Nobue, Shimamura Kazuo, Matsuzaki Shohei, Mine Tetsuya
Abstract excerpt
We report a case of fatal liver failure due to reactivation of lamivudine-resistant HBV. A 53-year-old man was followed since 1998 for HBV-related chronic hepatitis. Serum HBV-DNA was 150 MEq/mL (branched DNA signal amplification assay) and ALT levels fluctuated between 50-200 IU/L with no clinical signs of liver cirrhosis. Lamivudine (100 mg/d) was started in May 2001 and serum HBV-DNA subsequently decreased...
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