Article
Sensitivity to radiation-induced chromosome damage may be a marker of genetic predisposition in young head and neck cancer patients.
British journal of cancer - 23 Mar 2001
Papworth R, Slevin N, Roberts S A, Scott D
Abstract excerpt
We previously showed that levels of chromosome damage induced by ionizing radiation were, on average, higher in G(2)and G(0)lymphocytes of breast cancer patients than of normal healthy controls, but that there was no correlation between the results in the two assays. We proposed that enhanced sensitivity to G(2)or G(0)irradiation was a marker of low-penetrance predisposition to breast cancer, and have recently...
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