Article
Disease-stage variance in functional CD4(+) T-cell responses against novel pan-human leukocyte antigen-D region presented human papillomavirus-16 E7 epitopes.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2004
Warrino Dominic E, Olson Walter C, Knapp William T, Scarrow Meera I, D'Ambrosio-Brennan Lori J, Guido Richard S, Edwards Robert P, Kast W Martin, Storkus Walter J
Abstract excerpt
Given the anticipated clinical importance of helper and regulatory CD4(+) T cells reactive against human papillomavirus-16 E7 in the cervical carcinoma setting, we performed this study to identify novel E7-derived T helper (Th) epitopes and to characterize functional anti-E7 Th responses in normal donors and patients with cervical intraepithelial neoplasia I-III or cervical cancer. Candidate pan-HLA-DR (D region)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.