Article
Cytotoxic T-lymphocyte responses to human papillomavirus type 16 E5 and E7 proteins and HLA-A*0201-restricted T-cell peptides in cervical cancer patients.
Journal of virology - 1 Mar 2007
Liu Dai-Wei, Yang Yuh-Cheng, Lin Ho-Fan, Lin Mei-Fang, Cheng Ya-Wen, Chu Chen-Chung, Tsao Yeou-Ping, Chen Show-Li
Abstract excerpt
Previously, we found that human papillomavirus type 16 (HPV-16) E5 protein is a tumor rejection antigen and can induce cytotoxic T-lymphocyte (CTL) activity. Therefore, in this study, human leukocyte antigen A*0201 (HLA-A*0201)-restricted human CTL epitopes of HPV-16 E5 protein were identified using a bioinformatics approach, and the abilities of these predicted peptides to induce an immune response in HLA-A*0201...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
