Article
Genome scan analyses and positional cloning strategy in IBD: successes and limitations.
Best practice & research. Clinical gastroenterology - 1 Jun 2004
Wild Gary E, Rioux John D
Abstract excerpt
The past decade has witnessed a tremendous expansion of our knowledge-base of genetics of inflammatory bowel disease. To a large extent, this progress reflects the scientific innovation and impact of the human genome project, which has fueled many laboratory-based studies focusing on the molecular genetics of Crohn's disease and ulcerative colitis. The complementary strategies of genome-wide linkage scanning and...
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