Article

Validation of a CRISPR/cas9-based technology platform for examining specific immune gene functions in an experimental murine model of IBD

2019-04-26

Abstract excerpt

Inflammatory bowel diseases (IBD) are complex, multifactorial disorders characterized by chronic relapsing intestinal inflammation. Association studies have identified hundreds of genes that are linked to IBD and potentially regulate its pathology. The further dissection of the genetic network underlining IBD pathogenesis and pathophysiology is hindered by the limited capacity to investigate the role of each GWAS...

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Identifiers and source

Literature Corpus work: d81490db-2ce2-54b2-9121-f1146c6cee25
DOI: 10.1101/619791

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