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Article

Microdissection-based genotyping assists discrimination of reactive gliosis from glioma.

American journal of clinical pathology - 1 May 2004

Finkelstein Sydney D, Mohan Deepak, Hamilton Ronald L, Sasatomi Eizaburo, Swalsky Patricia A, Lieberman Frank S

Abstract excerpt

We used molecular anatomic pathology to determine the mutational status (loss of heterozygosity [LOH]) to make the distinction between reactive gliosis and glial neoplasia. LOH has been shown to be absent in reactive states and present in neoplastic cellular proliferations. Three groups of patient specimens were analyzed: group 1, reactive gliosis (n = 15); group 2, gliomas of varying histologic type and grade (n...

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Identifiers

PMID: 15151207
DOI: 10.1309/WF2H-L03T-7YP7-13NK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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