Article
Promoter polymorphisms of tumor necrosis factor-alpha are associated with risk of gastric mucosa-associated lymphoid tissue lymphoma.
International journal of cancer - 10 Jul 2004
Wu Ming-Shiang, Chen Li-Tzong, Shun Chia-Tung, Huang Shih-Pei, Chiu Han-Mo, Wang Hsiu-Po, Lin Ming-Tsang, Cheng Ann-Lii, Lin Jaw-Town
Abstract excerpt
Genes involved in regulating antimicrobial immunity and inflammation may modulate the risk of Helicobacter pylori-associated diseases. IL-1 and TNF-alpha are major cytokines detected in H. pylori-infected tissues. We aimed to determine the role of gene polymorphisms for these cytokines and their receptors in 2 distinct H. pylori-related gastric malignancies, adenocarcinoma (GAC) and maltoma. Genotyping for...
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